Boris Johnson has travelled to the West Country with his family, but No 10 insists that he is not on holiday.
It comes after the Prime Minister cut short his summer break in Somerset earlier this month after Kabul fell to the Taliban.
He came under fire for going away as the crisis in Afghanistan intensified.
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Mr Johnson left Downing Street on Sunday for a few days in the countryside with his wife Carrie and their young son Wilfred, reports The Mirror.
His spokesman insisted that the PM was still working as normal when criticised whether he should be taking a holiday while some British nationals are still stuck in Afghanistan.
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The PM’s official spokesman said: “The Prime Minister is away for the next two days in the West of England but he is continuing to work and will be back in the office in Downing Street on Thursday.
“He left on Sunday, I believe.”
Asked if it was a holiday, the spokesman said: “He is away, as I say, out of the office for a couple of days but he is working.”
Asked if it was appropriate for PM to be away from No 10 while British nationals are still stuck in Afghanistan, the spokesman said: “He continues to lead the overall Government response to the situation in Afghanistan.”
Mr Johnson and Foreign Secretary Dominic Raab were both on holiday when the Taliban took control of the Afghan capital on August 15.
The PM returned to London after just one day away in Somerset while Mr Raab came under fire for not coming back earlier from a break in Crete.